Article
Aging and lymphocyte subsets in the spleen and peripheral blood of the Sprague-Dawley rat.
Immunopharmacology and immunotoxicology - 1 May 1997
Flaherty D K, Wagner C A, Gross C J, Panyik M A
Abstract excerpt
This study was undertaken to determine the effects of aging on lymphocyte subsets in the peripheral blood and spleens of Sprague-Dawley rats. Rats aged 3,13 and 26 months were used in the study. Analyses of dual labeled lymphocytes from the 26 month animals show decreases in the numbers of lymphocytes due to decreased cellularity (spleen) or reduced lymphocyte percentages within the total white blood cell...
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