Article
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on humoral immunity and lymphocyte subpopulations: differences between mice and rats.
Toxicology and applied pharmacology - 1 Feb 1994
Smialowicz R J, Riddle M M, Williams W C, Diliberto J J
Abstract excerpt
While the effect that TCDD has on humoral immunity has been well documented for the mouse, it has not been for the rat. In this study, the effect that TCDD has on the antibody plaque-forming cell (PFC) response to sheep red blood cells (SRBC) in adult female B6C3F1 mice and F344 rats was compared...
Topics
- Animals
- Antibody Formation
- Cytochrome P-450 Enzyme System
- Female
- Lymphocytes
- Male
- Mice
- Microsomes, Liver
- Phenotype
- Polychlorinated Dibenzodioxins
- Rats
- Rats, Inbred F344
- Species Specificity
- Spleen