Article
Effects of thyroid hormones on the lymphocyte phenotypes in rats: changes in lymphocyte subsets related to thyroid function.
Endocrine regulations - 1 Sept 1994
Ohashi H, Itoh M
Abstract excerpt
The effects of hyperthyroidism and hypothyroidism on the immune function were assessed in rats by the changes in lymphocyte subsets in peripheral blood and spleen. Hyperthyroidism was induced in rats by intraperitoneal injection of large doses of T4. Hypothyroid rats were prepared by total thyroidectomy followed by 131I administration. In the hyperthyroid rats, the peripheral blood helper/suppressor T cell ratio...
Topics
- Animals
- Dose-Response Relationship, Drug
- Female
- Flow Cytometry
- Hyperthyroidism
- Hypothyroidism
- Immune System
- Lymphocyte Activation
- Lymphocyte Subsets
- Male
- Phenotype