Article
The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex.
Molecular and cellular biology - 1 Apr 1997
Jiang R, Carlson M
Abstract excerpt
The Snf1 protein kinase plays a central role in the response to glucose starvation in the yeast Saccharomyces cerevisiae. Previously, we showed that two-hybrid interaction between Snf1 and its activating subunit, Snf4, is inhibited by high levels of glucose. These findings, together with biochemical evidence that Snf1 and Snf4 remain associated in cells grown in glucose, suggested that another protein (or...
Topics
- AMP-Activated Protein Kinases
- Amino Acid Sequence
- Binding Sites
- Carrier Proteins
- Conserved Sequence
- Fungal Proteins
- Glucose
- Models, Biological
- Molecular Sequence Data
- Mutation
- Plant Proteins
- Protein Conformation
- Protein Kinases