Article
Regulation of the nucleocytoplasmic distribution of Snf1-Gal83 protein kinase.
Eukaryotic cell - 1 Dec 2006
Hedbacker Kristina, Carlson Marian
Abstract excerpt
Snf1 protein kinase containing the beta subunit Gal83 is localized in the cytoplasm during growth of Saccharomyces cerevisiae cells in abundant glucose and accumulates in the nucleus in response to glucose limitation. Nuclear localization of Snf1-Gal83 requires activation of the Snf1 catalytic subunit and depends on Gal83, but in the snf1Delta mutant, Gal83 exhibits glucose-regulated nuclear accumulation. We show...
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