Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

beta-subunits of Snf1 kinase are required for kinase function and substrate definition.

The EMBO journal - 15 Sept 2000

Schmidt M C, McCartney R R

Abstract excerpt

The Snf1 kinase and its mammalian homolog, the AMP-activated protein kinase, are heterotrimeric enzymes composed of a catalytic alpha-subunit, a regulatory gamma-subunit and a beta-subunit that mediates heterotrimer formation. Saccharomyces cerevisiae encodes three beta-subunit genes, SIP1, SIP2 and GAL83. Earlier studies suggested that these subunits may not be required for Snf1 kinase function. We show here...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AMP-Activated Protein Kinases
Share to Basic-Leucine Zipper Transcription Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to beta-Fructofuranosidase

Share to Epitopes

Share to Genetic Complementation Test

Share to Glucose

Share to Glycoside Hydrolases

Share to Trans-Activators

Source

Open in PubMed Open full text

Identifiers

PMID: 10990457
DOI: 10.1093/emboj/19.18.4936
PMCID: PMC314222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

beta-subunits of Snf1 kinase are required for kinase function and substrate definition.PMID 10990457Read ↗

Purification and characterization of Snf1 kinase complexes containing a defined Beta subunit composition.Semantic proximity Read ↗

The beta-subunits of the Snf1 kinase in Saccharomyces cerevisiae, Gal83 and Sip2, but not Sip1, are redundant in glucose derepression and regulation of sterol biosynthesis.Semantic proximity Read ↗

A Suppressor Mutation in the β-Subunit Kis1 Restores Functionality of the SNF1 Complex in Candida albicans snf4Δ Mutants.Semantic proximity Read ↗

Protein kinase A contributes to the negative control of Snf1 protein kinase in Saccharomyces cerevisiae.Semantic proximity Read ↗

Heterotrimer-independent regulation of activation-loop phosphorylation of Snf1 protein kinase involves two protein phosphatases.Semantic proximity Read ↗

Relationship of the cAMP-dependent protein kinase pathway to the SNF1 protein kinase and invertase expression in Saccharomyces cerevisiae.Semantic proximity Read ↗

Regulation of Snf1 kinase. Activation requires phosphorylation of threonine 210 by an upstream kinase as well as a distinct step mediated by the Snf4 subunit.Semantic proximity Read ↗

Feedback Control of Snf1 Protein and Its Phosphorylation Is Necessary for Adaptation to Environmental Stress.Semantic proximity Read ↗

Roles of the glycogen-binding domain and Snf4 in glucose inhibition of SNF1 protein kinase.Semantic proximity Read ↗

The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex.Semantic proximity Read ↗

Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth.Semantic proximity Read ↗

Roles of two protein phosphatases, Reg1-Glc7 and Sit4, and glycogen synthesis in regulation of SNF1 protein kinase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.