Article
Domain fusion between SNF1-related kinase subunits during plant evolution.
EMBO reports - 1 Jan 2001
Lumbreras V, Alba M M, Kleinow T, Koncz C, Pagès M
Abstract excerpt
Members of the conserved SNF1/AMP-activated protein kinase (AMPK) family regulate cellular responses to environmental and nutritional stress in eukaryotes. Yeast SNF1 and animal AMPKs form a complex with regulatory SNF4/AMPKgamma and SIP1/SIP2/GAL83/AMPKbeta subunits. The beta-subunits function as target selective adaptors that anchor the catalytic kinase and regulator SNF4/gamma-subunits to their kinase...
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