TP53 protein accumulation and gene mutation in relation to overexpression of MDM2 protein in ovarian borderline tumours and stage I carcinomas.

doi:10.1002/(SICI)1096-9896(199702)181:2<158::AID-PATH742>3.0.CO;2-8

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Article

TP53 protein accumulation and gene mutation in relation to overexpression of MDM2 protein in ovarian borderline tumours and stage I carcinomas.

The Journal of pathology - 1 Feb 1997

Skomedal H, Kristensen G B, Abeler V M, Børresen-Dale A L, Tropé C, Holm R

Abstract excerpt

Three hundred and seventy-four early-stage ovarian tumours, including 27 borderline tumours and 347 stage I carcinomas, were investigated immunohistochemically for overexpression of the TP53 and MDM2 proteins. TP53 (p53) and MDM2 alterations were detected in 15 and 4 per cent of borderline tumour...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
DNA, Neoplasm
Disease-Free Survival
Female
Gene Expression
Genes, p53
Humans
Immunoenzyme Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Neoplasm Proteins

Nuclear Proteins

Ovarian Neoplasms

Proto-Oncogene Proteins

Source

Open in PubMed

Identifiers

PMID: 9120719
DOI: 10.1002/(SICI)1096-9896(199702)181:2<158::AID-PATH742>3.0.CO;2-8

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9120719-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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