Article
Bcl-2 and p53 protein expression, apoptosis, and p53 mutation in human epithelial ovarian cancers.
The American journal of pathology - 1 Feb 2000
Chan W Y, Cheung K K, Schorge J O, Huang L W, Welch W R, Bell D A, Berkowitz R S, Mok S C
Abstract excerpt
Bcl-2 and p53 gene products have been both linked to cell death by apoptosis. In the present study, we examined the relationship of Bcl-2 and p53 protein expression, p53 mutation and apoptosis in normal human ovaries and different types of human ovarian epithelial tumors by immunohistochemical localization, in situ terminal transferase-mediated dUTP nick end labeling and polymerase chain reaction-single strand...
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