Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<i>mdm2</i> gene alterations and mdm2 protein expression in breast carcinomas

1 Jan 1995

Abstract excerpt

This study investigates the mdm2 gene status and expression in 66 surgically resected human breast carcinomas, with correlations with clinico-pathological and biological data (histological type, grading, steroid receptor status, p53 expression, proliferative activity). Four (7.7 per cent) out of 52 informative cases bear mdm2 gene amplification (four-to ten-fold) and 8 (15.4 per cent) of 52 cases showed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Cancer-related Molecular Pathways
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7891224
DOI: 10.1002/path.1711750106

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<i>mdm2</i> gene alterations and mdm2 protein expression in breast carcinomasPMID 7891224Read ↗

Amplification of the MDM2 gene in human breast cancer and its association with MDM2 and p53 protein statusSemantic proximity Read ↗

The MDM2 gene amplification databaseSemantic proximity Read ↗

MDM2 gene amplification in human breast cancerSemantic proximity Read ↗

Overexpression of the<i>MDM2</i>Oncogene in Leukemia and LymphomaSemantic proximity Read ↗

Amplification of Mdmx and overexpression of MDM2 contribute to mammary carcinogenesis by substituting for p53 mutations.Semantic proximity Read ↗

p53 expression and relationship with MDM2 amplification in breast carcinomas.Semantic proximity Read ↗

Prognostic Relevance of Gene Amplifications and Coamplifications in Breast CancerSemantic proximity Read ↗

Overexpression of MDM2 oncoprotein correlates with possession of estrogen receptor alpha and lack of MDM2 mRNA splice variants in human breast cancerSemantic proximity Read ↗

p53-Independent Activities of MDM2 and Their Relevance to Cancer TherapySemantic proximity Read ↗

Activation of multiple cancer-associated genes at the <i>ERBB2</i> amplicon in breast cancerSemantic proximity Read ↗

Targeting MDM2-p53 interaction for breast cancer therapySemantic proximity Read ↗

MDM2 gene amplification is correlated to tumor progression but not to the presence of SNP309 or TP53 mutational status in primary colorectal cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.