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Article

p53 gene analysis of ovarian borderline tumors and stage I carcinomas.

Human pathology - 1 Apr 1995

Kupryjanczyk J, Bell D A, Dimeo D, Beauchamp R, Thor A D, Yandell D W

Abstract excerpt

Mutations of the p53 gene are common in human ovarian carcinomas; however, their role in the early development of ovarian cancer is unclear. Twelve ovarian borderline tumors (BTs; eight of them p53 immunopositive) and 10 stage I carcinomas (four of them p53 immunopositive) were studied for genetic alterations in the p53 gene. The study was based on single-strand conformation polymorphism (SSCP) analysis and DNA...

Topics

Adult
Aged
Female
Genes, p53
Humans
Immunohistochemistry
Middle Aged
Mutation
Neoplasm Staging
Ovarian Neoplasms
Polymorphism, Single-Stranded Conformational
Tumor Suppressor Protein p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7705816
DOI: 10.1016/0046-8177(95)90138-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7705816-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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