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Article

Overexpression and mutation of p53 in epithelial ovarian cancer.

Cancer research - 1 Jun 1991

Marks J R, Davidoff A M, Kerns B J, Humphrey P A, Pence J C, Dodge R K, Clarke-Pearson D L, Iglehart J D, Bast R C, Berchuck A

Abstract excerpt

We examined p53 expression in 107 epithelial ovarian cancers with immunohistochemical techniques using monoclonal antibody PAb1801. High level expression of nuclear p53 protein was detected in the malignant epithelium in 54 (50%) of these cancers. Expression of p53 protein was undetectable in 13 benign gynecological tissues. p53 mRNA from three cancers that overexpressed the protein were sequenced and point...

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PMID: 2032235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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