Article
Inflammatory cytokines inhibit upregulation of glycolipid expression by Schwann cells in vitro.
Neurology - 1 Dec 1998
Lisak R P, Bealmear B, Benjamins J, Skoff A
Abstract excerpt
OBJECTIVE: To determine whether products of inflammatory cells can inhibit differentiation and synthesis of myelin glycolipids by Schwann cells. BACKGROUND: Infiltration of the peripheral nervous system by inflammatory cells is a feature of acquired demyelinating neuropathies. It is not clear wha...
Topics
- 8-Bromo Cyclic Adenosine Monophosphate
- Animals
- Animals, Newborn
- Cell Differentiation
- Cell Division
- Cells, Cultured
- Cyclic AMP
- Cytarabine
- Cytokines
- Demyelinating Diseases
- Glycolipids
- Immunosuppressive Agents
- Myelin Proteins
- Phenotype
- Rats
- Rats, Sprague-Dawley
- Schwann Cells
- Sciatic Nerve
