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Article

Inflammatory cytokines inhibit upregulation of glycolipid expression by Schwann cells in vitro.

Neurology - 1 Dec 1998

Lisak R P, Bealmear B, Benjamins J, Skoff A

Abstract excerpt

OBJECTIVE: To determine whether products of inflammatory cells can inhibit differentiation and synthesis of myelin glycolipids by Schwann cells. BACKGROUND: Infiltration of the peripheral nervous system by inflammatory cells is a feature of acquired demyelinating neuropathies. It is not clear what role these cells have in causing demyelination or inhibiting myelin synthesis. METHODS: Nonmyelinating rat Schwann...

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PMID: 9855519
DOI: 10.1212/wnl.51.6.1661

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