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Article

Schwann Cell Transplantation Subdues the Pro-Inflammatory Innate Immune Cell Response after Spinal Cord Injury.

International journal of molecular sciences - 28 Aug 2018

Pearse Damien D, Bastidas Johana, Izabel Sarah S, Ghosh Mousumi

Abstract excerpt

The transplantation of Schwann cells (SCs) has been shown to provide tissue preservation and support axon growth and remyelination as well as improve functional recovery across a diverse range of experimental spinal cord injury (SCI) paradigms. The autologous use of SCs has progressed to Phase 1 SCI clinical trials in humans where their use has been shown to be both feasible and safe. The contribution of immune...

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Source

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Identifiers

PMID: 30154346
DOI: 10.3390/ijms19092550
PMCID: PMC6163303

Genes

TNF

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