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Article

Lipopolysaccharide induces human interleukin-1 receptor antagonist and interleukin-1 production in the same cell.

European journal of immunology - 1 Oct 1992

Andersson J, Björk L, Dinarello C A, Towbin H, Andersson U

Abstract excerpt

A new member of the interleukin-1 (IL-1) family has recently been described. Human IL-1 receptor antagonist (IL-1ra) is structurally related to IL-1 alpha and IL-1 beta but binds to IL-1 receptors on various target cells without demonstrable agonist activity. Understanding the mechanisms of regulation of IL-1ra production may clarify the biology of this unique cytokine as well as elucidate its possible role as a...

Topics

Adult
Cells, Cultured
Humans
Interleukin 1 Receptor Antagonist Protein
Interleukin-1
Lipopolysaccharides
Phenotype
Sialoglycoproteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1396967
DOI: 10.1002/eji.1830221022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1396967-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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