Article
A role for interleukin-1 in epidermal differentiation: regulation by expression of functional versus decoy receptors.
Journal of cell science - 1 Aug 1995
Eller M S, Yaar M, Ostrom K, Harkness D D, Gilchrest B A
Abstract excerpt
Although human epidermis contains levels of interleukin-1 (IL-1) up to 100 times higher than other tissues, the role of this cytokine in epidermal biology is unknown. Here, we show that interleukin-1 regulates the expression of mRNAs for two proteins associated with the differentiated phenotype o...
Topics
- Base Sequence
- Cell Differentiation
- Cells, Cultured
- Cornified Envelope Proline-Rich Proteins
- DNA Primers
- DNA Probes
- Gene Expression Regulation
- Humans
- Infant, Newborn
- Interleukin-1
- Keratinocytes
- Male
- Membrane Proteins
- Molecular Sequence Data
- Phenotype
- Polymerase Chain Reaction
- Protein Biosynthesis
- Proteins