Relationship of anticardiolipin antibodies and antiphospholipid syndrome to HLA-DR7 in Mexican patients with systemic lupus erythematosus (SLE).

doi:10.1177/096120339700600108

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Article

Relationship of anticardiolipin antibodies and antiphospholipid syndrome to HLA-DR7 in Mexican patients with systemic lupus erythematosus (SLE).

Lupus - 1 Jan 1997

Granados J, Vargas-Alarcón G, Drenkard C, Andrade F, Melín-Aldana H, Alcocer-Varela J, Alarcón-Segovia D

Abstract excerpt

We studied IgG and IgM anticardiolipin antibodies (aCL) by an ELISA method in 80 Mexican systemic lupus erythematosus (SLE) patients and 378 of their first degree relatives. Sixty five percent of SLE patients and 16% of their relatives were positive for aCL. We also determined allele and haplotyp...

Topics

Alleles
Antibodies, Anticardiolipin
Antiphospholipid Syndrome
Enzyme-Linked Immunosorbent Assay
Female
Gene Frequency
HLA-DQ Antigens
HLA-DR3 Antigen
HLA-DR7 Antigen
Haplotypes
Humans
Immunoglobulin G
Immunoglobulin M
Lupus Erythematosus, Systemic
Male
Mexico
Pedigree

Source

Open in PubMed

Identifiers

PMID: 9116720
DOI: 10.1177/096120339700600108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9116720-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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