Article
MHC gene products and anticardiolipin antibodies in systemic lupus erythematosus results of a multicenter study. SLE Study Group.
Autoimmunity - 1 Jan 1992
Hartung K, Coldewey R, Corvetta A, Deicher H, Kalden J R, Krapf F, Lang B, Lakomek H J, Liedvogel B, Peter H H
Abstract excerpt
Anticardiolipin antibodies (aCL) and HLA-DR antigens were determined in 314 central European patients with systemic lupus erythematosus (SLE). Both HLA-DR4 and DR7 were increased in aCL-positive patients, and aCL were significantly associated with DRw53. The association between DRw53 and aCL was...
Topics
- Antibodies, Anticardiolipin
- Antiphospholipid Syndrome
- Autoimmune Diseases
- Disease Susceptibility
- Europe
- Genetic Predisposition to Disease
- HLA Antigens
- Humans
- Immunoglobulin G
- Immunoglobulin M
- Lupus Erythematosus, Systemic
- Major Histocompatibility Complex
- White People