Article
Construction, expression and preliminary characterization of glycosylation mutants of human protein S.
Polish journal of pharmacology - 1 Jan 2000
Rydzewski A, Myśliwiec M, Long G L
Abstract excerpt
Human protein S (HPS) is a vitamin K dependent plasma glycoprotein involved in the regulation of activated protein C and possibly fibrinolysis. Its c-DNA sequence shows three N-glycosylation consensus sequences (Asn-X-Ser/Thr). In order to study influence of N-linked glycosylation on HPS function, set of mutants of HPS was constructed. Mutants were generated, starting from an SV40/Adeno derived pD5HPS2 expression...
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