Construction, expression and preliminary characterization of glycosylation mutants of human protein S.

Article

Construction, expression and preliminary characterization of glycosylation mutants of human protein S.

Polish journal of pharmacology - 1 Jan 2000

Rydzewski A, Myśliwiec M, Long G L

Abstract excerpt

Human protein S (HPS) is a vitamin K dependent plasma glycoprotein involved in the regulation of activated protein C and possibly fibrinolysis. Its c-DNA sequence shows three N-glycosylation consensus sequences (Asn-X-Ser/Thr). In order to study influence of N-linked glycosylation on HPS function...

Topics

Base Sequence
Cells, Cultured
DNA Primers
DNA, Complementary
Glycosylation
Humans
In Vitro Techniques
Kidney
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Protein S
Transfection

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