[Clinical significance of multidrug resistance in acute leukemias].

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Article

[Clinical significance of multidrug resistance in acute leukemias].

Revista da Associacao Medica Brasileira (1992) - 1 Jan 2000

Maia R C, Rumjanek V M

Abstract excerpt

A significant number of patients with acute leukaemias fail in their treatment as a result of the development of resistance to chemotherapy. Several evidences indicate that the expression of a mdr 1 gen, which codifies for P glycoprotein (PgP), contributes to this resistance in leukaemic cells. P...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Adolescent
Adult
Antineoplastic Agents
Blood Cells
Child
Child, Preschool
Cyclosporine
Drug Resistance, Multiple
Humans
Idarubicin
Infant
Leukemia, Myeloid
Phenotype
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Prognosis
Recurrence
Rhodamines

Source

Open in PubMed

Identifiers

PMID: 9110459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9110459-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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