Article
Multidrug resistance in acute myeloid leukaemia.
Bailliere's clinical haematology - 1 Mar 1996
Sonneveld P
Abstract excerpt
Multidrug resistance represents a form of pleiotropic drug resistance that has a prognostic value in untreated AML. It may affect the outcome of current chemotherapy protocols. Therefore, MDR1 expression should be systematically investigated in prospective studies. In addition, restoration of drug sensitivity may be attempted by adding drug resistance modifying agents such as cyclosporins to standard...
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