Multidrug resistance in acute myeloid leukaemia.

doi:10.1016/s0950-3536(96)80043-6

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Article

Multidrug resistance in acute myeloid leukaemia.

Bailliere's clinical haematology - 1 Mar 1996

Sonneveld P

Abstract excerpt

Multidrug resistance represents a form of pleiotropic drug resistance that has a prognostic value in untreated AML. It may affect the outcome of current chemotherapy protocols. Therefore, MDR1 expression should be systematically investigated in prospective studies. In addition, restoration of dru...

Topics

Acute Disease
Antimetabolites, Antineoplastic
Cytarabine
DNA Topoisomerases, Type II
Drug Resistance, Multiple
Drug Resistance, Neoplasm
Humans
Leukemia, Myeloid
Phenotype

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