Article
Insertion/deletion polymorphism on ACE gene is associated with endothelial dysfunction in young patients with hypertension.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Sept 2006
Penesova A, Cizmarova E, Kvetnansky R, Koska J, Sedlakova B, Krizanova O
Abstract excerpt
Endothelial dysfunction, insulin resistance (IR) and genetic predispositions are important risk factors of hypertension. Aim of our study was to test the hypothesis, whether insertion/deletion (I/D) polymorphism on the angiotensin converting enzyme (ACE) gene and M235T polymorphism on angiotesinogen gene (AGT) correlates with parameters of insulin sensitivity and plasminogen activator inhibitor (PAI-1) levels in...
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