Article
Exercise-induced changes in insulin action are associated with ACE gene polymorphisms in older adults.
Physiological genomics - 29 Oct 2002
Dengel Donald R, Brown Michael D, Ferrell Robert E, Reynolds Thomas H, Supiano Mark A
Abstract excerpt
We evaluated the association between insulin resistance and the angiotensin-converting enzyme (ACE) insertion (I)/deletion (D) gene polymorphism in a group of older hypertensive subjects (63 +/- 1 yr, n = 35) before and after a 6-mo aerobic exercise program (AEX). Insulin sensitivity index (S(I)), assessed by the frequently sampled intravenous glucose tolerance test, was significantly (P = 0.0001) increased...
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