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Article

A schizophrenia locus may be located in region 10p15-p11.

American journal of medical genetics - 10 Jul 1998

Straub R E, MacLean C J, Martin R B, Ma Y, Myakishev M V, Harris-Kerr C, Webb B T, O'Neill F A, Walsh D, Kendler K S

Abstract excerpt

In our genomic scan of 265 Irish families with schizophrenia, we have thus far generated modest evidence for the presence of vulnerability genes in three chromosomal regions, i.e., 5q21-q31, 6p24-p22, and 8p22-p21. Outside of those regions, of all markers tested to date, D10S674 produced one of t...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 10
Female
Genetic Linkage
Genetic Markers
Genotype
Humans
Ireland
Lod Score
Male
Pedigree
Schizophrenia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9674974
DOI: 10.1002/(sici)1096-8628(19980710)81:4<296::aid-ajmg4>3.0.co;2-s

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9674974-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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A schizophrenia locus may be located in region 10p15-p11.PMID 9674974Read ↗

Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish families.Semantic proximity Read ↗

Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes.Semantic proximity Read ↗

Further evidence for a susceptibility locus on chromosome 10p14-p11 in 72 families with schizophrenia by nonparametric linkage analysis.Semantic proximity Read ↗

Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23.Semantic proximity Read ↗

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