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Article

Role of specific amino acid residues in T4 endonuclease V that alter nontarget DNA binding.

Biochemistry - 8 Apr 1997

Nyaga S G, Dodson M L, Lloyd R S

Abstract excerpt

Endonuclease V is a pyrimidine dimer-specific DNA glycosylase-apurinic (AP)1 lyase which, in vivo or at low salt concentrations in vitro, binds nontarget DNA through electrostatic interactions and remains associated with that DNA until all dimers have been recognized and incised. On the basis of the analyses of previous mutants that effect this processive nicking activity, and the recently published cocrystal...

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PMID: 9100001
DOI: 10.1021/bi962218x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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