Article
RIC1, a novel gene required for ribosome synthesis in Saccharomyces cerevisiae.
Gene - 18 Mar 1997
Mizuta K, Park J S, Sugiyama M, Nishiyama M, Warner J R
Abstract excerpt
We isolated a temperature-sensitive mutant of Saccharomyces cerevisiae in which transcription both of ribosomal protein genes and of ribosomal RNA is defective at the non-permissive temperature. Temperature-sensitivity for growth is recessive and segregates 2:2. The wild type gene, termed RIC1 (for ribosome control) was cloned by complementation of the temperature-sensitive phenotype from a genomic DNA library...
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