Article
Antigen presentation by common variable immunodeficiency (CVID) B cells and monocytes is unimpaired.
Clinical and experimental immunology - 1 Apr 1997
Thon V, Eggenbauer H, Wolf H M, Fischer M B, Litzman J, Lokaj J, Eibl M M
Abstract excerpt
CVID is a primary immunodeficiency syndrome comprising a heterogeneous group of patients with hypogammaglobulinaemia and defective formation of specific antibodies. Previous studies demonstrated defective T cell responsiveness to antigen in a major subgroup of patients. In the present study we in...
Topics
- Antigen Presentation
- Antigen-Presenting Cells
- Antigens
- B-Lymphocytes
- Cell Line
- Cell Line, Transformed
- Common Variable Immunodeficiency
- Genes, MHC Class II
- Humans
- Monocytes
- Phenotype
- T-Lymphocytes
- Tetanus Toxoid