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Article

Molecular mechanism underlying the action of a novel fusion inhibitor of influenza A virus.

Journal of virology - 1 May 1997

Luo G, Torri A, Harte W E, Danetz S, Cianci C, Tiley L, Day S, Mullaney D, Yu K L, Ouellet C, Dextraze P, Meanwell N, Colonno R, Krystal M

Abstract excerpt

In the initial stages of influenza virus infection, the hemagglutinin (HA) protein of influenza virus mediates both adsorption and penetration of the virus into the host cell. Recently, we identified and characterized BMY-27709 as an inhibitor of the H1 and H2 subtypes of influenza A virus that specifically inhibits the HA function necessary for virus-cell membrane fusion (G.-X. Luo, R. Colonno, and M. Krystal,...

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Identifiers

PMID: 9094684
DOI: 10.1128/JVI.71.5.4062-4070.1997
PMCID: PMC191559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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