Characterization of a hemagglutinin-specific inhibitor of influenza A virus.

doi:10.1006/viro.1996.0628

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Article

Characterization of a hemagglutinin-specific inhibitor of influenza A virus.

Virology - 1 Dec 1996

Luo G, Colonno R, Krystal M

Abstract excerpt

A novel inhibitor of influenza virus growth in tissue culture was identified and characterized. This compound (BMY-27709) has an IC50 of 3-8 microM for A/WSN/33 virus growth in a multicycle replication assay and is active against all H1 and H2 subtype viruses tested. However, BMY-27709 was found...

Topics

Animals
Benzamides
Cattle
Cell Line
Chickens
Dogs
Drug Resistance, Microbial
Hemagglutinin Glycoproteins, Influenza Virus
Hemolytic Plaque Technique
Humans
Influenza A virus
Phenotype
Transfection
Virus Replication

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