Article
An induced pocket for the binding of potent fusion inhibitor CL-385319 with H5N1 influenza virus hemagglutinin.
PloS one - 1 Jan 2012
Li Runming, Song Deshou, Zhu Zhibo, Xu Hanhong, Liu Shuwen
Abstract excerpt
The influenza glycoprotein hemagglutinin (HA) plays crucial roles in the early stage of virus infection, including receptor binding and membrane fusion. Therefore, HA is a potential target for developing anti-influenza drugs. Recently, we characterized a novel inhibitor of highly pathogenic H5N1...
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