The TNF2 allele does not contribute towards susceptibility to systemic lupus erythematosus.

doi:10.1016/s0165-2478(96)02635-1

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Article

The TNF2 allele does not contribute towards susceptibility to systemic lupus erythematosus.

Immunology letters - 1 Jan 1997

Chen C J, Yen J H, Tsai W C, Wu C S, Chiang W, Tsai J J, Liu H W

Abstract excerpt

The uncommon allele (TNF2) of a polymorphism in the promoter region of the tumor necrosis factor-alpha (TNF-alpha) gene has been reported to be increased in Caucasian systemic lupus erythematosus (SLE) patients (associated with HLA-DR3). To investigate whether TNF2 contributes towards susceptibility to Chinese SLE patients (not associated with HLA-DR3), 100 patients with SLE and 107 controls were studied. The...

Topics

Alleles
Asian People
Autoimmune Diseases
China
Disease Susceptibility
Female
Gene Frequency
Genotype
HLA-DR3 Antigen
Humans
Lupus Erythematosus, Systemic
Male
Tumor Necrosis Factor-alpha
White People

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PMID: 9093873
DOI: 10.1016/s0165-2478(96)02635-1

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