Article
Relationship of tumour necrosis factor alpha gene polymorphisms and neuropsychiatric lupus.
Lupus - 1 Jan 2002
May L A, Huang Q, Morris D, Danis V, Manolios N
Abstract excerpt
Systemic lupus erythematosus (SLE) is a multisystem disorder which appears to be influenced by genetic make-up. In this study we determine allele frequency and genotype distribution of TNFalpha polymorphisms in two populations of SLE patients (with and without neuropsychiatric manifestations) in order to determine whether the rare allele (TNF2) confers susceptibility for neuropsychiatric disease in SLE. Patients...
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