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Article

Isolation and characterization of suppressors of two Escherichia coli dnaG mutations, dnaG2903 and parB.

Genetics - 1 Apr 1997

Britton R A, Lupski J R

Abstract excerpt

The dnaG gene of Escherichia coli encodes the primase protein, which synthesizes a short pRNA that is essential for the initiation of both leading and lagging strand DNA synthesis. Two temperature-sensitive mutations in the 3' end of the dnaG gene, dnaG2903 and parB, cause a defect in chromosome partitioning at the nonpermissive temperature 42 degrees. We have characterized 24 cold-sensitive suppressor mutations...

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Identifiers

PMID: 9093842
DOI: 10.1093/genetics/145.4.867
PMCID: PMC1207892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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