Isolation and characterization of suppressors of two Escherichia coli dnaG mutations, dnaG2903 and parB.

doi:10.1093/genetics/145.4.867

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Article

Isolation and characterization of suppressors of two Escherichia coli dnaG mutations, dnaG2903 and parB.

Genetics - 1 Apr 1997

Britton R A, Lupski J R

Abstract excerpt

The dnaG gene of Escherichia coli encodes the primase protein, which synthesizes a short pRNA that is essential for the initiation of both leading and lagging strand DNA synthesis. Two temperature-sensitive mutations in the 3' end of the dnaG gene, dnaG2903 and parB, cause a defect in chromosome...

Topics

Alleles
Bacterial Proteins
Cold Temperature
DNA Primase
DNA, Bacterial
DNA, Recombinant
Escherichia coli
Genes, Bacterial
Genes, Suppressor
Genetic Complementation Test
RNA Nucleotidyltransferases
Sequence Analysis, DNA

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