Article
Missense mutations in the 3' end of the Escherichia coli dnaG gene do not abolish primase activity but do confer the chromosome-segregation-defective (par) phenotype.
Microbiology (Reading, England) - 1 Feb 1997
Versalovic James, Lupski James R
Abstract excerpt
Isogenic dnaG strains of Escherichia coli with the parB and dnaG2903 alleles in the MG1655 chromosomal background displayed the classic par phenotype at the nonpermissive temperature of 42 degrees C. These strains synthesized DNA at 42 degrees C, but remained chromosome segregation defective as d...
Topics
- Alleles
- Bacterial Proteins
- Chromosomes, Bacterial
- DNA Primase
- DNA Replication
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Proteins
- Genes, Bacterial
- Mutation
- Phenotype
- RNA Nucleotidyltransferases
- SOS Response, Genetics
- Serine Endopeptidases