Article
Functional analysis of mutations in the transcription terminator T1 that suppress two dnaG alleles in Escherichia coli.
Molecular & general genetics : MGG - 20 Mar 1995
Britton R A, Lupski J R
Abstract excerpt
The mutations dnaG2903 and parB are both temperature-sensitive conditional lethal alleles of the Escherichia coli dnaG gene, which encodes the protein primase. The lesions are located in the 3' end of the gene, 9 basepairs apart, and both cause Glu-to-Lys substitutions in the carboxy terminus of primase. Previously, it was shown that dnaG2903 can be suppressed by point mutations in the rho-independent...
Topics
- Alleles
- Base Sequence
- DNA Primase
- Escherichia coli
- Genes, Bacterial
- Molecular Sequence Data
- Phenotype
- Point Mutation
- RNA Nucleotidyltransferases
- Suppression, Genetic
- Terminator Regions, Genetic