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Article

Dynamic multidrug therapies for HIV: a control theoretic approach.

Journal of theoretical biology - 7 Mar 1997

Wein L M, Zenios S A, Nowak M A

Abstract excerpt

Motivated by the inability of current drug treatment to provide long-term benefit to HIV-infected individuals, we derive HIV therapeutic strategies by formulating and analyzing a mathematical control problem. The model tracks the dynamics of uninfected and infected CD4+ cells and free plasma virus, and allows the virus to mutate into various strains. At each point in time, several different therapeutic options...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9093552
DOI: 10.1006/jtbi.1996.0253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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