Article
Dynamic multidrug therapies for HIV: a control theoretic approach.
Journal of theoretical biology - 7 Mar 1997
Wein L M, Zenios S A, Nowak M A
Abstract excerpt
Motivated by the inability of current drug treatment to provide long-term benefit to HIV-infected individuals, we derive HIV therapeutic strategies by formulating and analyzing a mathematical control problem. The model tracks the dynamics of uninfected and infected CD4+ cells and free plasma viru...
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