Article
Polymorphism of platelet membrane glycoprotein IIIa: human platelet antigen 1b (HPA-1b/PlA2) is an inherited risk factor for premature myocardial infarction in coronary artery disease.
Thrombosis and haemostasis - 1 Apr 1998
Zotz R B, Winkelmann B R, Nauck M, Giers G, Maruhn-Debowski B, März W, Scharf R E
Abstract excerpt
Conflicting results of an association between the human platelet antigen 1b (HPA-1b or PlA2) allele and the risk of myocardial infarction and coronary artery disease have been reported. To assess the reason for this discrepancy, we determined the HPA-1 genotype in 298 men who had undergone corona...
Topics
- Adult
- Age of Onset
- Antigens, Human Platelet
- Coronary Disease
- Coronary Thrombosis
- Disease Susceptibility
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Myocardial Infarction
- Platelet Glycoprotein GPIIb-IIIa Complex
- Polymorphism, Genetic