Rac is required for growth cone function but not neurite assembly.

doi:10.1242/jcs.110.5.635

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Article

Rac is required for growth cone function but not neurite assembly.

Journal of cell science - 1 Mar 1997

Lamoureux P, Altun-Gultekin Z F, Lin C, Wagner J A, Heidemann S R

Abstract excerpt

Recent work has suggested that rac1 and other members of the rho family of small GTP-binding proteins play an important role in the formation of neural processes. We have explored the mechanism of this effect by comparing the spontaneous, growth cone-mediated growth and experimental tension-induc...

Topics

Animals
Axons
Cell Division
GTP-Binding Proteins
Genes, Dominant
Microscopy, Fluorescence
Mutation
Nerve Growth Factors
Neurites
PC12 Cells
Rats
rac GTP-Binding Proteins

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