Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Computer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signaling.

The Journal of cell biology - 4 Jan 2016

Fusco Ludovico, Lefort Riwal, Smith Kevin, Benmansour Fethallah, Gonzalez German, Barillari Caterina, Rinn Bernd, Fleuret Francois, Fua Pascal, Pertz Olivier

Abstract excerpt

Rho guanosine triphosphatases (GTPases) control the cytoskeletal dynamics that power neurite outgrowth. This process consists of dynamic neurite initiation, elongation, retraction, and branching cycles that are likely to be regulated by specific spatiotemporal signaling networks, which cannot be resolved with static, steady-state assays. We present NeuriteTracker, a computer-vision approach to automatically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice
Share to Neurites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to rhoA GTP-Binding Protein

Share to Signal Transduction

Share to Spatio-Temporal Analysis

Share to Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 26728857
DOI: 10.1083/jcb.201506018
PMCID: PMC4700477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Computer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signaling.PMID 26728857Read ↗

IgCAMs: bidirectional signals underlying neurite growthSemantic proximity Read ↗

Identification of neural outgrowth genes using genome-wide RNAi.Semantic proximity Read ↗

Rac GTPases control axon growth, guidance and branching.Semantic proximity Read ↗

Rho and Ras GTPases in axon growth, guidance, and branching.Semantic proximity Read ↗

A deep learning approach to neurite prediction in high throughput fluorescence imagingSemantic proximity Read ↗

Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracingSemantic proximity Read ↗

Reggies/flotillins regulate cytoskeletal remodeling during neuronal differentiation via CAP/ponsin and Rho GTPases.Semantic proximity Read ↗

A Modular Platform for the Optogenetic Control of Small GTPase Activity in Living Cells Reveals Long-Range RhoA SignalingSemantic proximity Read ↗

Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screenSemantic proximity Read ↗

Phenotypes of Drosophila brain neurons in primary culture reveal a role for fascin in neurite shape and trajectory.Semantic proximity Read ↗

Quantification of local morphodynamics and local GTPase activity by edge evolution tracking.Semantic proximity Read ↗

The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.