Article
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor.
Nature - 9 Apr 1998
York R D, Yao H, Dillon T, Ellig C L, Eckert S P, McCleskey E W, Stork P J
Abstract excerpt
Activation of mitogen-activated protein (MAP) kinase (also known as extracellular-signal-regulated kinase, or ERK) by growth factors can trigger either cell growth or differentiation. The intracellular signals that couple growth factors to MAP kinase may determine the different effects of growth...
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