Article
K+ channel expression and cell proliferation are regulated by intracellular sodium and membrane depolarization in oligodendrocyte progenitor cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Apr 1997
Knutson P, Ghiani C A, Zhou J M, Gallo V, McBain C J
Abstract excerpt
The effects of a variety of antiproliferative agents on voltage-dependent K+ channel function in cortical oligodendrocyte progenitor (O-2A) cells were studied. Previously, we had shown that glutamate receptor activation reversibly inhibited O-2A cell proliferation stimulated by mitogenic factors and prevented lineage progression by attenuating outward K+ currents in O-2A cells. We now show that the...
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