Article
Converting amino acid alignment scores into measures of evolutionary time: a simulation study of various relationships.
Journal of molecular evolution - 1 Apr 1997
Feng D F, Doolittle R F
Abstract excerpt
Amino acid substitution tables are essential for the proper alignment of protein sequences, and alignment scores based on them can be transformed into distance measures by various means. In the simplest case, the negative log of the score is used. This Poisson relationship assumes that all sites...
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