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Article

Applications of codon and rate variation models in molecular phylogeny.

Molecular biology and evolution - 1 Sept 2002

Schadt Eric E, Sinsheimer Janet S, Lange Kenneth

Abstract excerpt

The current article illustrates the practical advantages of some new models and statistical algorithms for codon substitution and spatial rate variation in molecular phylogeny. Our companion paper in this issue discusses at length the mathematical properties of these models for nucleotide and codon substitution, for site-to-site and branch-to-branch heterogeneity in rates of evolution, and for spatial correlation...

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PMID: 12200482
DOI: 10.1093/oxfordjournals.molbev.a004217

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