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Article

Myeloma stem cell concepts, heterogeneity and plasticity of multiple myeloma

20 Sept 2013

Abstract excerpt

Multiple myeloma (MM) is a haematological malignancy characterized by the accumulation of clonal plasma cells (PCs) in the bone marrow (BM). Although novel therapeutic strategies have prolonged survival of patients, the disease remains difficult to treat with a high risk of relapse. The failure of therapy is thought to be associated with a persistent population of the so-called MM stem cells or myeloma initiating...

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PMID: 24111932
DOI: 10.1111/bjh.12563

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