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Article

Multiple Myeloma: A Paradigm for Translation of the Cancer Stem Cell Hypothesis

1 Feb 2010

Abstract excerpt

Despite recent advances in drug development, multiple myeloma (MM) remains incurable for the majority of patients due to relapse and disease progression. The cancer stem cell (CSC) hypothesis may provide an explanation for these clinical findings. It suggests that the long-term proliferative potential responsible for disease initiation, maintenance, and relapse is contained within specific subpopulations of...

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PMID: 20184542
DOI: 10.2174/187152010790909344

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