Article
Protein and DNA requirements of the bacteriophage HP1 recombination system: a model for intasome formation.
Nucleic acids research - 1 Oct 2001
Esposito D, Thrower J S, Scocca J J
Abstract excerpt
A fundamental step in site-specific recombination reactions involves the formation of properly arranged protein-DNA structures termed intasomes. The contributions of various proteins and DNA binding sites in the intasome determine not only whether recombination can occur, but also in which direction the reaction is likely to proceed and how fast the reaction will go. By mutating individual DNA binding sites and...
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