Metabolic ratios of four probes of CYP2D6 in Turkish subjects: a cross-over study.

doi:10.1007/BF03189732

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Article

Metabolic ratios of four probes of CYP2D6 in Turkish subjects: a cross-over study.

European journal of drug metabolism and pharmacokinetics - 1 Jan 2000

Bozkurt A, Basçi N E, Işimer A, Sayal A, Kayaalp S O

Abstract excerpt

The relationships among the metabolic ratios for the standard probe drugs of CYP2D6 activity, such as debrisoquine, sparteine, metoprolol and dextromethorphan, were studied in 32 Turkish subjects. All subjects were randomly selected according to their phenotypes from a group of 111 Turkish subjec...

Topics

Adult
Cross-Over Studies
Cytochrome P-450 CYP2D6
Debrisoquin
Dextromethorphan
Female
Humans
Male
Metoprolol
Middle Aged
Phenotype
Sparteine
Turkey

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