Article
Metabolic ratios of four probes of CYP2D6 in Turkish subjects: a cross-over study.
European journal of drug metabolism and pharmacokinetics - 1 Jan 2000
Bozkurt A, Basçi N E, Işimer A, Sayal A, Kayaalp S O
Abstract excerpt
The relationships among the metabolic ratios for the standard probe drugs of CYP2D6 activity, such as debrisoquine, sparteine, metoprolol and dextromethorphan, were studied in 32 Turkish subjects. All subjects were randomly selected according to their phenotypes from a group of 111 Turkish subjects whose oxidation status had been tested for debrisoquine previously. All subjects were given a 10 mg debrisoquine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
