Article
Mutations in the Saccharomyces cerevisiae type 2A protein phosphatase catalytic subunit reveal roles in cell wall integrity, actin cytoskeleton organization and mitosis.
Genetics - 1 Feb 1997
Evans D R, Stark M J
Abstract excerpt
Temperature-sensitive mutations were generated in the Saccharomyces cerevisiae PPH22 gene that, together with its homologue PPH21, encode the catalytic subunit of type 2A protein phosphatase (PP2A). At the restrictive temperature (37 degrees), cells dependent solely on pph22 alleles for PP2A func...
Topics
- Actins
- Alleles
- Catalysis
- Cell Wall
- Cytoskeleton
- Fungal Proteins
- Microtubules
- Mitosis
- Morphogenesis
- Mutation
- Phenotype
- Phosphoprotein Phosphatases
- Saccharomyces cerevisiae