The role of Saccharomyces cerevisiae type 2A phosphatase in the actin cytoskeleton and in entry into mitosis.

doi:10.1002/j.1460-2075.1995.tb07275.x

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Article

The role of Saccharomyces cerevisiae type 2A phosphatase in the actin cytoskeleton and in entry into mitosis.

The EMBO journal - 15 Jun 1995

Lin F C, Arndt K T

Abstract excerpt

We have prepared a temperature-sensitive Saccharomyces cerevisiae type 2A phosphatase (PP2A) mutant, pph21-102. At the restrictive temperature, the pph21-102 cells arrested predominantly with small or aberrant buds, and their actin cytoskeleton and chitin deposition were abnormal. The involvement of PP2A in bud growth may be due to the role of PP2A in actin distribution during the cell cycle. Moreover, after a...

Topics

Actins
Amino Acid Sequence
Base Sequence
CDC28 Protein Kinase, S cerevisiae
Cell Cycle Proteins
Chitin
Cyclin B
Cyclins
Cytoskeleton
Fungal Proteins
G2 Phase
Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Fungal

Mitosis

Molecular Sequence Data

Mutation

Phosphoprotein Phosphatases

Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 7796803
DOI: 10.1002/j.1460-2075.1995.tb07275.x
PMCID: PMC398393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7796803-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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