Article
Effects of deletion of different PP2C protein phosphatase genes on stress responses in Saccharomyces cerevisiae.
Yeast (Chichester, England) - 1 Oct 2014
Sharmin Dilruba, Sasano Yu, Sugiyama Minetaka, Harashima Satoshi
Abstract excerpt
A key mechanism of signal transduction in eukaryotes is reversible protein phosphorylation, mediated through protein kinases and protein phosphatases (PPases). Modulation of signal transduction by this means regulates many biological processes. Saccharomyces cerevisiae has 40 PPases, including seven protein phosphatase 2C (PP2C PPase) genes (PTC1-PTC7). However, their precise functions remain poorly understood....
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